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The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development m

Pediatric neurology. --- Nervous System Diseases. --- Child. --- Adolescent. --- Nervous system --- Neurology --- Diseases

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The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Even diseases more often encountered in adulthood than childhood may have specific expression in the developing nervous system. The course of chronic neurological diseases beginning before adolescence remains distinct from that of adult pathology - not only from the cognitive but also motor perspective, right into adulthood, and a whole area is developing for adult neurologists to care for these children with persisting neurological diseases when they become adults. Just as pediatric neurology evolved as an identified specialty as the volume and complexity of data became too much for the general pediatician or the adult neurologist to master, the discipline has now continued to evolve into so many subspecialties, such as epilepsy, neuromuscular disease, stroke, malformations, neonatal neurology, metabolic diseases, etc., that the general pediatric neurologist no longer can reasonably possess in-depth expertise in all areas, particularly in dealing with complex cases. Subspecialty expertise thus is provided to some trainees through fellowship programmes following a general pediatric neurology residency and many of these fellowships include training in research. Since the infectious context, the genetic background and medical practice vary throughout the world, this diversity needs to be represented in a pediatric neurology textbook. Taken together, and although brain malformations (H. Sarnat & P. Curatolo, 2007) and oncology (W. Grisold & R. Soffietti) are covered in detail in other volumes of the same series and therefore only briefly addressed here, these considerations justify the number of volumes, and the number of authors who contributed from all over the world. Experts in the different subspecialties also contributed to design the general framework and contents of the book. Special emphasis is given to the developmental aspect, and normal development is reminded whenever needed - brain, muscle and the immune system. The course of chronic diseases into adulthood and ethical issues specific to the developing nervous system are also addressed. *A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology. *International list of contributors including the leading workers in the field. *Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care.

Paediatrics --- Neuropathology

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« «Si mon enfant doit garder des séquelles, je préférerais qu'il meure. » Que de fois ai-je entendu ces paroles de détresse, cet affolement devant l'impossible nouvelle, à l'annonce du diagnostic d'une épilepsie grave et probablement incurable ! Ce n'est que quand les parents acceptent de regarder leur enfant comme un être «différent», que tout change. Seuls témoins de la crise, ils deviennent alors source irremplaçable de connaissance ; j'ai appris à les écouter. Ces enfants oubliés de l'industrie pharmaceutique et de bien des services sociaux ont bouleversé ma vie. Ils m'ont tant appris sur leur maladie, sur eux-mêmes, sur les parents, sur la façon de parler avec les autres, sur des questions éthiques, sur le développement du cerveau, et sur la société en général.» OLIVIER DULAC. « Olivier Dulac nous invite à écouter ces remémorations scientifiques et humaines qui font de nous les témoins d'une discipline - la neuropédiatrie - et d'un champ de connaissances - les épilepsies de l'enfant - qui auront connu des bouleversements fulgurants. » DENIS PIVETEAU. Ce livre s'adresse avant tout aux parents de ces petits, mais aussi aux médecins qui sont amenés à les voir, aux enseignants de la médecine, aux acteurs de l'industrie pharmaceutique, aux responsables des programmes « santé » dans les médias, de l'OMS et de toutes les ONG concernées, et tous ceux que le développement du cerveau intéresse.

Enfants épileptiques --- Épilepsie --- Épilepsie. --- Malformations corticales. --- Epilepsy --- Central Nervous System Diseases --- Parent-Child Relations